Five-star Hotels in Panama

Last updated on May 17, 2023

We have found 27 five-star hotel deals in Panama. Below are the most elegant and luxurious stays in Panama. Enter your dates to find the best luxury hotel for your stay.

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Decapolis Hotel Panama City

Decapolis Hotel Panama City

The luxorious Decapolis Hotel Panama City is a 5 star hotel located at Avenida Balboa-Multicentro in In city centre. The hotel is rated as Very good with score of 8.2, based on 6674 hotel reviews.

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  • City Center
  • 5 Stars
  • 8.2 Very good
Available rooms
Riu Plaza Panamá

Riu Plaza Panamá

This great stay is a 5 star hotel located at Calle 50 con 53 Este, Marbella in Bella Vista 450 m from centre. The hotel is rated as Fabulous with score of 8.7, based on 10195 hotel reviews.

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  • 5 Stars
  • 8.7 Fabulous
Available rooms
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

The beautiful Hotel El Panama by Faranda Grand, a member of Radisson Individuals is a 5 star hotel located at Via España 111 in Bella Vista 1 km from centre. The hotel is rated as Good with score of 7.9, based on 2050 hotel reviews.

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  • 5 Stars
  • 7.9 Good
Available rooms
Global Hotel Panama

Global Hotel Panama

Luxorious and elegant, the Global Hotel Panama is a 5 star hotel located at Calle 54 Este y Avenida Samuel Lewis, Obarrio in Bella Vista 0.9 km from centre. The hotel is rated as Fabulous with score of 8.7, based on 1932 hotel reviews.

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  • 5 Stars
  • 8.7 Fabulous
Available rooms
Megapolis Hotel Panama

Megapolis Hotel Panama

Elegant and stylish, the Megapolis Hotel Panama is a 5 star hotel located at Avenida Balboa Boulevard Elhayek in In city centre. The hotel is rated as Very good with score of 8.2, based on 1998 hotel reviews.

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  • City Center
  • 5 Stars
  • 8.2 Very good
Available rooms
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

Providing a great value, the Waymore Hotel Spa & Casino is a 5 star hotel located at Avenida Eusebio A. Morales in Bella Vista 1.2 km from centre. The hotel is rated as Fabulous with score of 8.7, based on 955 hotel reviews.

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  • 5 Stars
  • 8.7 Fabulous
Available rooms
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

The elegant Bristol Panama, a Registry Collection Hotel is a 5 star hotel located at Calle Aquilino de la Guarida in Bella Vista 0.7 km from centre. The hotel is rated as Superb with score of 9.2, based on 1218 hotel reviews.

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  • 5 Stars
  • 9.2 Superb
Available rooms
Gran Evenia Panamá Hotel

Gran Evenia Panamá Hotel

One of my favorites, the Gran Evenia Panamá Hotel is a 5 star hotel located at Calle Eusebio A. Morales Esquina Calle Augusto Samuel Boyd-Urb El Cangrejo in Bella Vista 1.2 km from centre. The hotel is rated as Fabulous with score of 8.7, based on 1219 hotel reviews.

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  • 5 Stars
  • 8.7 Fabulous
Available rooms
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Providing a relaxing stay, the Central Hotel Panama Casco Viejo is a 5 star hotel located at Casco Antiguo, Avenida Central calle 5ta in Casco Viejo 3.2 km from centre. The hotel is rated as Very good with score of 8.4, based on 1587 hotel reviews.

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  • 5 Stars
  • 8.4 Very good
Available rooms
Hotel San Felipe

Hotel San Felipe

The gorgeous Hotel San Felipe is a 5 star hotel located at Ave. Central entre calle 8a y 9a in Casco Viejo 3.2 km from centre. The hotel is rated as Fabulous with score of 8.9, based on 367 hotel reviews.

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  • 5 Stars
  • 8.9 Fabulous
Available rooms
Hotel Las Americas Golden Tower Panamá

Hotel Las Americas Golden Tower Panamá

Providing one of the best stays, the hotel is a 5 star hotel located at Avenida Balboa con Calle 53 esquina, Marbella, Panama in In city centre. The hotel is rated as Very good with score of 8.5, based on 1813 hotel reviews.

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  • City Center
  • 5 Stars
  • 8.5 Very good
Available rooms
Intercontinental Miramar Panama by IHG

Intercontinental Miramar Panama by IHG

The luxorious Intercontinental Miramar Panama by IHG is a 5 star hotel located at Balboa Avenue, Plaza Miramar in Bella Vista 0.7 km from centre. The hotel is rated as Very good with score of 8, based on 472 hotel reviews.

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  • 5 Stars
  • 8 Very good
Available rooms
Sheraton Grand Panama

Sheraton Grand Panama

This great stay is a 5 star hotel located at Vía Israel y Calle 77 San Francisco in 2.5 km from centre. The hotel is rated as Fabulous with score of 8.6, based on 1143 hotel reviews.

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  • 5 Stars
  • 8.6 Fabulous
Available rooms
Hyatt Regency Panama City

Hyatt Regency Panama City

The beautiful Hyatt Regency Panama City is a 5 star hotel located at Calle 52 and Ricardo Arias in Bella Vista 0.7 km from centre. The hotel is rated as Superb with score of 9.1, based on 11 hotel reviews.

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  • 5 Stars
  • 9.1 Superb
Available rooms
Radisson Hotel Panama Canal

Radisson Hotel Panama Canal

Luxorious and elegant, the Radisson Hotel Panama Canal is a 5 star hotel located at Boulevard Amador, Avenida Pelicano in Ancon 5.6 km from centre. The hotel is rated as Very good with score of 8.2, based on 3070 hotel reviews.

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  • 5 Stars
  • 8.2 Very good
Available rooms
The Santa Maria, a Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, a Luxury Collection Hotel & Golf Resort, Panama City

Elegant and stylish, the The Santa Maria, a Luxury Collection Hotel & Golf Resort, Panama City is a 5 star hotel located at Santa Maria Boulevard in 9.1 km from centre. The hotel is rated as Superb with score of 9.3, based on 522 hotel reviews.

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  • 5 Stars
  • 9.3 Superb
Available rooms
American Trade Hotel

American Trade Hotel

Providing a great value, the American Trade Hotel is a 5 star hotel located at Plaza Herrera, Casco Viejo in Casco Viejo 3.3 km from centre. The hotel is rated as Fabulous with score of 8.7, based on 599 hotel reviews.

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  • 5 Stars
  • 8.7 Fabulous
Available rooms
Hotel La Compania, In The Unbound Collection By Hyatt

Hotel La Compania, In The Unbound Collection By Hyatt

The elegant Hotel La Compania, In The Unbound Collection By Hyatt is a 5 star hotel located at Avenida A, Esquina Calle 8, Casco Antiguo in Casco Viejo 3.3 km from centre. The hotel is rated as Exceptional with score of 9.5, based on 454 hotel reviews.

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  • 5 Stars
  • 9.5 Exceptional
Available rooms
Le Meridien Panama

Le Meridien Panama

One of my favorites, the Le Meridien Panama is a 5 star hotel located at Calle Uruguay y Avenida Balboa in Bella Vista 0.5 km from centre. The hotel is rated as Very good with score of 8, based on 261 hotel reviews.

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  • 5 Stars
  • 8 Very good
Available rooms
JW Marriott Panama

JW Marriott Panama

Providing a relaxing stay, the JW Marriott Panama is a 5 star hotel located at Calle Punta Colon, Punta Pacífica in Punta Pacifica 1.5 km from centre. The hotel is rated as Fabulous with score of 8.8, based on 937 hotel reviews.

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  • 5 Stars
  • 8.8 Fabulous
Available rooms
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